Results: A statement of the results that can be gleaned from the particular figure However, in certain instances, such as in Nature manuscripts with a methods section, journal editors may request that this information not be detailed in the figure legends. This information should be limited to what is absolutely necessary to understand the figure without referring to the paper’s methods section. This description could include the cell type or animal model, the conditions/treatments tested, the control(s) used, the laboratory and statistical tests applied, and the numbers of replicates and repeats. Materials and methods: A description of the techniques used In some cases, this title may be partly or entirely drawn from a subheading in the results section of the paper. The title can be either descriptive, stating the type of experiment(s) (e.g., “Flow cytometry analysis of US6-expressing cells”), or declarative, asserting the overall finding (e.g., “The viral protein US6 decreases MHC I surface expression”). Title: A brief title that applies to the entire figure, including all panels The following are components that should be included in your figure legend. Due to this need to be independent from the rest of the text, the structure of a legend may somewhat resemble that of a pared-down paper, including a title and short descriptions of both the methods and the results. Overall, the content of a caption should make it possible for your reader to interpret and understand the significance of a figure without reading the main text. Although standards for writing legends vary from journal to journal, there are a few common principles that may help to ensure clarity. Figures are instrumental for conveying your results but may be inscrutable without an effective legend.
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